Hox-D8 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5760
Background:
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD8 functions as a sequence-specific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
Alternative Name:
Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4, Name: HOXD8, HOX4E, Hox-5.4,
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: Hox-D8 polyclonal antibody detects endogenous levels of Hox-D8 protein.
Immunogen:
Synthetic peptide, corresponding to the 245-290 of Human Hox-D8.
MW: ~ 32 kDa
Swis Prot.: P13378
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD8 functions as a sequence-specific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.
Alternative Name:
Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4, Name: HOXD8, HOX4E, Hox-5.4,
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: Hox-D8 polyclonal antibody detects endogenous levels of Hox-D8 protein.
Immunogen:
Synthetic peptide, corresponding to the 245-290 of Human Hox-D8.
MW: ~ 32 kDa
Swis Prot.: P13378
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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