HOXA1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
HOXA1(HOMEOBOX A1), also called HOMEOBOX 1F, is a protein that in humans is encoded by the HOXA1 gene. In PA-1 teratocarcinoma cells, HOXA1 was induced by retinoic acid earlier than other HOXA cluster genes. The HOXA1 gene is mapped on 7p15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. A common polymorphism in the HOXA1 gene is associated with a susceptibility to autism spectrum disorder. Three-dimensional reconstructions of Hoxa1 -/- rhombencephalon revealed that it bears only 5 rhombomeric structures instead of the normal 7. A single maternal administration of a low dose of the vitamin A metabolite retinoic acid was sufficient to compensate the requirement for Hoxa1 function in Hoxa1-deficient mice.

Description:
Rabbit IgG polyclonal antibody for Homeobox protein Hox-A1 (HOXA1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
BSAS antibody, Homeo box A1 antibody, Homeobox 1F antibody, Homeobox A1 antibody, Homeobox protein Hox A1 antibody, Homeobox protein Hox-1F antibody, Homeobox protein Hox-A1 antibody, Hox 1.6 like protein antibody, Hox 1F antibody, HOX A1 antibody, HOX A1 homeodomain protein antibody, Hox-1F antibody, HOX1 antibody, HOX1F antibody, hoxa1 antibody, hoxb1b antibody, HXA1_HUMAN antibody, Lab like protein antibody, MGC45232 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human HOXA1(1-15aa MDNARMNSFLEYPIL), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human HOXA1(1-15aa MDNARMNSFLEYPIL), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.