HOXA10 Polyclonal Antibody

Background:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
HOXA10, HOX1, HOX1.8, HOX1H, PL

Immunogen: Recombinant fusion protein of human HOXA10 (NP_061824.3).

Swissprot: P31260
Gene ID: 3206

Calculated MW: 11 kDa/42 kDa
Observed MW: 53 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.