HOXB8 polyclonal (C-term), anti-human

HOXB8 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP16167b
Catalog Number: AC-AP16167b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35492
Applications: WB
Datasheet

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Background:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Other Names:
Homeobox protein Hox-B8, Homeobox protein Hox-24, Homeobox protein Hox-2D, HOXB8, HOX2D

Target/Specificity:
This HOXB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human HOXB8.

Antigen Region:
215-243

Antigen Type: Synthetic Peptide

Gene Name: HOXB8
Gene ID: 3218
Primary Accession: P17481
NCBI Accession: NP_076921.1
Other Accession: NP_076921.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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