HOXC10 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60596
Background:
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC10 oscillates in abundance during the cell cycle, being targeted for degradation early in mitosis by the ubiquitin-dependent proteasome pathway. HoxC10 is a homeoprotein with the potential to influence mitotic progression, and might provide a link between developmental regulation and cell cycle control.
Alternative Name:
Homeobox protein Hox-C10, Homeobox protein Hox-3I, HOXC10, HOX3I
Application Dilution: WB: 1:500~1:1000
Specificity: HOXC10 polyclonal antibody detects endogenous levels of HOXC10 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human HOXC10
MW: ~ 38 kDa
Swis Prot.: Q9NYD6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxC10 oscillates in abundance during the cell cycle, being targeted for degradation early in mitosis by the ubiquitin-dependent proteasome pathway. HoxC10 is a homeoprotein with the potential to influence mitotic progression, and might provide a link between developmental regulation and cell cycle control.
Alternative Name:
Homeobox protein Hox-C10, Homeobox protein Hox-3I, HOXC10, HOX3I
Application Dilution: WB: 1:500~1:1000
Specificity: HOXC10 polyclonal antibody detects endogenous levels of HOXC10 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human HOXC10
MW: ~ 38 kDa
Swis Prot.: Q9NYD6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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