HOXD10 polyclonal, anti-human

Background:
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as rocker-bottom foot deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Other Names:
Homeobox protein Hox-D10, Homeobox protein Hox-4D, Homeobox protein Hox-4E, HOXD10, HOX4D, HOX4E

Antigen Types:
Synthetic Peptide

Gene Name:
HOXD10
Gene ID:
3236
Primary Accession: P28358
Other Accession: NP_002139;3236;15430 (mouse); 303991 (rat);