HOXD11 Polyclonal Antibody

Background:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
Homeo box 4F, Homeo box D11, Homeobox D11, Homeobox protein Hox-4F, Homeobox protein Hox-D11, Hox-4F, HOX4, HOX4F, HOXD11, HXD11

Immunogen: Synthetic peptide of human HOXD11

Swissprot: P31277
Gene Accession: NP_067015

Calculated MW: 34 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:1000-1:3000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-82919