HOXD12 Blocking Peptide (C-term)

Background:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.

Other Names:
Homeobox D12, isoform CRA_a;HOXD12

Target/Specificity:
The synthetic peptide sequence is selected from aa 226-237 of HUMAN B5MCD3

Gene Name: B5MCD3
Primary Accession: B5MCD3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.