HoxD8 Polyclonal Antibody

Background:
homeobox D8(HOXD8) Homo sapiens This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],

Alternative Names:
HOXD8, HOX4E, Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4

Immunogen: The antiserum was produced against synthesized peptide derived from human HOXD8. AA range:241-290

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 32

GeneID: HOXD8

Storage: -20°C/1 year

NOTE: For Research Use Only