HOXD8 polyclonal (C-term), anti-human

Background:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.

Other Names:
Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-54, HOXD8, HOX4E

Target/Specificity:
This HOXD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-270 amino acids from the C-terminal region of human HOXD8.

Antigen Region:
243-270

Antigen Type: Synthetic Peptide

Gene Name: HOXD8
Gene ID: 3234
Primary Accession: P13378
NCBI Accession: NP_001186675.1;NP_062458.1
Other Accession: NP_062458.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.