HP1α polyclonal, anti- antibody
€305.00
In stock
SKU
AC-ABV11393-25
Catalog Number: AC-ABV11393-25
Size: 25 µg
Host: Rabbit IgG
Applications: WB, IF
Datasheet
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Size: 25 µg
Host: Rabbit IgG
Applications: WB, IF
Datasheet
Request Information
Background:
CBX5/HP1 alpha is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins.
Other Names:
HP1α, HP1A
Primary Accession: P45973
Gene Name: CBX5
Gene ID: 23468
CBX5/HP1 alpha is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at ‘Lys-9’, leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins.
Other Names:
HP1α, HP1A
Primary Accession: P45973
Gene Name: CBX5
Gene ID: 23468
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