HRG Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7327a
Background:
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Other Names:
Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRG, HRG
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7327a was selected from the N-term region of human HRG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HRG
Gene ID: 3273
Primary Accession: P04196
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Other Names:
Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRG, HRG
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7327a was selected from the N-term region of human HRG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HRG
Gene ID: 3273
Primary Accession: P04196
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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