HRG Polyclonal Antibody

Background:
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Research Area: Cardiovascular

Synonyms:
DKFZp779H1622, Histidine proline rich glycoprotein, Histidine rich glycoprotein, HPRG, HRGP, Thrombophilia due to elevated HRG

Immunogen: Synthetic peptide of human HRG

Swissprot: P04196
Gene Accession: NP_000403

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-47042/sc-47045