HRG polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP7327a
Catalog Number: AC-AP7327a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18729
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18729
Applications: IHC-P, WB
Datasheet
Request Information
Background:
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Other Names:
Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRG, HRG
Target/Specificity:
This HRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human HRG.
Antigen Region:
13-42
Antigen Type: Synthetic Peptide
Gene Name: HRG
Gene ID: 3273
Primary Accession: P04196
NCBI Accession: NP_000403.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Other Names:
Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRG, HRG
Target/Specificity:
This HRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human HRG.
Antigen Region:
13-42
Antigen Type: Synthetic Peptide
Gene Name: HRG
Gene ID: 3273
Primary Accession: P04196
NCBI Accession: NP_000403.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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