HRI (EIF2AK1) polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP8114c
Catalog Number: AC-AP8114c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12521
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12521
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme.
Other Names:
Eukaryotic translation initiation factor 2-alpha kinase 1, Heme-controlled repressor, HCR, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor, Hemin-sensitive initiation factor 2-alpha kinase, EIF2AK1, HRI, KIAA1369
Target/Specificity:
This HRI (EIF2AK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 amino acids from the Central region of human HRI (EIF2AK1).
Antigen Region:
267-296
Antigen Type: Synthetic Peptide
Gene Name: EIF2AK1 (HGNC:24921)
Gene ID: 27102
Primary Accession: Q9BQI3
NCBI Accession: NP_001127807.1;NP_055228.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The HRI gene is localized to 7p22 where its 3' end slightly overlaps the 3' end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme.
Other Names:
Eukaryotic translation initiation factor 2-alpha kinase 1, Heme-controlled repressor, HCR, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor, Hemin-sensitive initiation factor 2-alpha kinase, EIF2AK1, HRI, KIAA1369
Target/Specificity:
This HRI (EIF2AK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 amino acids from the Central region of human HRI (EIF2AK1).
Antigen Region:
267-296
Antigen Type: Synthetic Peptide
Gene Name: EIF2AK1 (HGNC:24921)
Gene ID: 27102
Primary Accession: Q9BQI3
NCBI Accession: NP_001127807.1;NP_055228.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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