HRPT2 polyclonal, anti-human

Quantity: 100 µg

Background:
Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Description:
Rabbit IgG polyclonal antibody for Parafibromin (CDC73) detection. Tested with WB in Human.

Synonyms:
C1orf28 antibody, CDC 73 antibody, Cdc73 antibody, CDC73_HUMAN antibody, Cell division cycle 73 antibody, Cell division cycle 73 Paf1/RNA polymerase II complex component homolog antibody, Cell division cycle protein 73 homolog antibody, FLJ23316 antibody, HPT JT antibody, HPTJT antibody, HRPT 2 antibody, Hyperparathyroidism 2 (with jaw tumor) antibody, Hyperparathyroidism 2 antibody, Hyperparathyroidism 2 protein antibody, HYX antibody, Parafibromin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.