Hrs (Phospho Tyr216) polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

Research Area: Cell biology, Signal transduction

Synonyms: Hepatocyte growth factor-regulated tyrosine kinase substrate, HGS, HRS, Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs, Protein pp110

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year