HSD11B1 / HDL polyclonal, anti-human

Background:
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

Other Names:
Corticosteroid 11-beta-dehydrogenase isozyme 1, 1.1.1.146, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1, HSD11B1, HSD11, HSD11L

Antigen Types:
Synthetic Peptide

Gene Name:
HSD11B1 (HGNC:5208)
Gene ID:
3290
Primary Accession: P28845
Other Accession: NP_861420;3290;