HSD11B1 polyclonal, anti-human, mouse, rat antibody
€310.00
In stock
SKU
AC-ABO10696
Catalog Number: AC-ABO10696
Size: 100 µg
Host: rabbit IgG
Applications: WB, IHC-P, IHC-F, ICC
Datasheet
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Size: 100 µg
Host: rabbit IgG
Applications: WB, IHC-P, IHC-F, ICC
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for Cystathionine beta-synthase (CBS) detection. Tested with WB, IHC-P in human, rat.
Protein Name: Cystathionine beta-synthase
Background:
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury (By similarity). .
Other Names:
Cystathionine beta-synthase, 4.2.1.22, Beta-thionase, Serine sulfhydrase, CBS
Subcellular Localization: Cytoplasm . Nucleus .
Tissue Specificity: In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.
Gene ID: 102724560;875
Immunogen: E.coli-derived human CBS recombinant protein (Position: A331-K551). Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS.
Calculated MW: 60587
Purification: Immunogen affinity purified.
Format: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Protein Name: Cystathionine beta-synthase
Background:
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury (By similarity). .
Other Names:
Cystathionine beta-synthase, 4.2.1.22, Beta-thionase, Serine sulfhydrase, CBS
Subcellular Localization: Cytoplasm . Nucleus .
Tissue Specificity: In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.
Gene ID: 102724560;875
Immunogen: E.coli-derived human CBS recombinant protein (Position: A331-K551). Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS.
Calculated MW: 60587
Purification: Immunogen affinity purified.
Format: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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