HSD17B12 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.

Synonyms: KAR, SDR12C1

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human HSD17B12

Gene Symbol: HSD17B12

Gene ID: 51144

Swiss prot: Q53GQ0

Calculated MW: 34kDa

Recommended dilution:
WB 1:1000-3000, IHC 1:25-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.