HSD17B2 polyclonal, anti-human

Background:
17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.

Synonyms: HSD17, SDR9C2, EDH17B2

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human HSD17B2

Gene Symbol: HSD17B2

Gene ID: 3294

Swiss prot: P37059

Calculated MW: 43kDa

Recommended dilution:
WB 1:25-200, IHC 1:25-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.