HSD17B2 Polyclonal Antibody

Background:
17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.

Research Area: Cancer, Signal Transduction

Synonyms:
17 beta HSD 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha HSD, 20 alpha hydroxysteroid dehydrogenase, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB2, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17, Hsd17b2, Hydroxysteroid (17 beta) dehydrogenase 2, Microsomal 17 beta hydroxysteroid dehydrogenase, Microsomal 17-beta-hydroxysteroid dehydrogenase, SDR9C2, Short chain dehydrogenase/reductase family 9C, member 2, Testosterone 17 beta dehydrogenase, Testosterone 17-beta-dehydrogenase

Immunogen: Recombinant protein of human HSD17B2

Swissprot: P37059
Gene Accession: BC009581

Calculated MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-66408