HSD17B2 Polyclonal Antibody

Background:
17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.

Research Area: Cancer, Signal Transduction

Synonyms:
HSD17B2, EDH17B2, HSD17, SDR9C2

Immunogen: Recombinant fusion protein of human HSD17B2 (NP_002144.1).

Swissprot: P37059
Gene ID: 3294

Calculated MW: 42 kDa
Observed MW: 47 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.