HSD17B4 Polyclonal Antibody

Background:
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, 17 beta HSD 4, 17 beta HSD IV, 17 beta hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, 17-beta-hydroxysteroid dehydrogenase 4, 17beta estradiol dehydrogenase type IV, 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase, 3-alpha, 7-alpha, Beta hydroxyacyl dehydrogenase, Beta keto reductase, D 3 hydroxyacyl CoA dehydratase, D bifunctional protein, D bifunctional protein peroxisomal, D-3-hydroxyacyl CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein, D-bifunctional protein, D-bifunctional protein, peroxisomal, DBP, DBP, peroxisomal, DHB4, EDH17B4, Enoyl-CoA hydratase 2, Hsd17b4, MFE 2, MFE-2, MPF-2, Multifunctional protein 2, Peroxisomal multifunctional enzyme type 2, Peroxisomal multifunctional protein 2, PRLTS1, SDR8C1, Short chain dehydrogenase/reductase family 8C member 1

Immunogen: Recombinant protein of human HSD17B4

Swissprot: P51659
Gene Accession: BC003098

Calculated MW: 80 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-66423