HSD17B8 Polyclonal Antibody

Background:
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Research Area: Neuroscience, Signal Transduction

Synonyms:
17 beta HSD 8, 17 beta hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, 17-beta-hydroxysteroid dehydrogenase 8, 17-beta-hydroxysteroid dehydrogenase VIII, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-oxoacyl-acyl-carrier protein reductase, E. coli, homolog of, Beta ketoacyl [acyl carrier protein] reductase like, D6S2245E, DHB8, dJ1033B10.9, Estradiol 17 beta dehydrogenase 8, Estradiol 17-beta-dehydrogenase 8, Estrogen 17 oxidoreductase, FABG, FabG, E. coli, homolog of, FabG-like, FABGL, H2 KE6, H2-KE6, HKE6, HSD17B8, Hydroxysteroid (17 beta) dehydrogenase 8, Ke-6, KE6, KE6, mouse homolog of, Protein Ke6, Really interesting new gene 2 protein, RING2, SDR30C1, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17 beta dehydrogenase 8, Testosterone 17-beta-dehydrogenase 8

Immunogen: Recombinant protein of human HSD17B8

Swissprot: Q92506
Gene Accession: BC008185

Calculated MW: 27 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-83768