HSD3B2 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7405
Background:
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
Alternative Name:
3 beta HSD adrenal and gonadal type, 3 beta HSD II, 3 beta HSD type II, 3 beta hydroxy 5 ene steroid dehydrogenase, 3 beta hydroxy Delta(5) steroid dehydrogenase, 3 beta hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, 3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, 3-beta-HSD II, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3BHS2_HUMAN, ADRENAL HYPERPLASIA II, beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, delta 5 delta 4 isomerase type II, Delta-5-3-ketosteroid isomerase, HSD3B, HSD3B2, HSDB, HSDB3B, hydroxy delta 5 steroid dehydrogenase, 3 beta and steroid delta isomerase 2, Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2, Progesterone reductase, SDR11E2, short chain dehydrogenase/reductase family 11E, member 2, Steroid Delta-isomerase,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: HSD3B polyclonal antibody detects endogenous levels of HSD3B protein.
Immunogen:
Recombinant full length Human HSD3B.
MW: ~42 kDa
Swis Prot.: P26439
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
Alternative Name:
3 beta HSD adrenal and gonadal type, 3 beta HSD II, 3 beta HSD type II, 3 beta hydroxy 5 ene steroid dehydrogenase, 3 beta hydroxy Delta(5) steroid dehydrogenase, 3 beta hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, 3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, 3-beta-HSD II, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3BHS2_HUMAN, ADRENAL HYPERPLASIA II, beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, delta 5 delta 4 isomerase type II, Delta-5-3-ketosteroid isomerase, HSD3B, HSD3B2, HSDB, HSDB3B, hydroxy delta 5 steroid dehydrogenase, 3 beta and steroid delta isomerase 2, Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2, Progesterone reductase, SDR11E2, short chain dehydrogenase/reductase family 11E, member 2, Steroid Delta-isomerase,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: HSD3B polyclonal antibody detects endogenous levels of HSD3B protein.
Immunogen:
Recombinant full length Human HSD3B.
MW: ~42 kDa
Swis Prot.: P26439
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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