HSD3B2 Polyclonal Antibody

Background:
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 2, 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II, Short Chain Dehydrogenase/Reductase Family 11E, Member 2, 3-Beta-HSD Adrenal And Gonadal Type, 3-Beta-HSD II, 3 Beta-Hydroxysteroid Dehydrogenase Type II, Delta 5-Delta 4-Isomerase Type II, 3 Beta-HSD Type II, 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2, 3-Beta-Hydroxy-Delta(5)-Steroid Dehydrogenase, 3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase.

Immunogen: Fusion protein of human HSD3B2

Swissprot: P26439
Gene Accession: BC038419

Calculated MW: 42 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.