HSF4 Polyclonal Antibody

Background:
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
Cataract, Marner, CTM, Heat shock factor protein 4, Heat shock transcription factor 4, hHSF4, HSF 4, HSF4, HSF4, HSTF 4

Immunogen: Synthetic peptide of human HSF4

Swissprot: Q9ULV5
Gene Accession: NP001529

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.