HSP-70 polyclonal, anti-human, mouse, rat

Protein Family: Chaperones and Folding Catalysts

Pathway and Disease: Immune System, Membrane Transport, Signal Transduction

Description:
HSP-70 (Heat shock 70 kDa protein 1) is a 70-kDa heat shock protein, a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, HSP-70 stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles. Heat shock proteins recognize non-native conformations of other proteins during translation and membrane translocation or following stress-induced damages. HSP-70 is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

Alternate Names: Heat shock 70 kDa protein 1, HSP70, HSP70.1, HSP70-1/HSP70-2, HSPA1A, HSPA1, HSPA1B

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P08107

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human HSP-70.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.