Hsp105/HSPH1 Picoband™ (clone 3D10), anti-human
€455.00
In stock
SKU
AC-ABO14879
Catalog Number: AC-ABO14879
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
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Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Description: Anti-Hsp105/HSPH1 Antibody Picoband™ (monoclonal, 3D10) . Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Protein Function:
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Other Names: Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, Heat shock protein family H member 1, HSPH1, HSP105, HSP110, KIAA0201
Clone Name(s):
Clone: 3D10
Subcellular Localization: Cytoplasm.
Tissue Specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Gene ID: 10808
Immunogen: E. coli-derived human Hsp105 recombinant protein (Position: Y653-D858).
Calculated MW: 96865
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): 0
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Other Names: Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, Heat shock protein family H member 1, HSPH1, HSP105, HSP110, KIAA0201
Clone Name(s):
Clone: 3D10
Subcellular Localization: Cytoplasm.
Tissue Specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Gene ID: 10808
Immunogen: E. coli-derived human Hsp105 recombinant protein (Position: Y653-D858).
Calculated MW: 96865
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): 0
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
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