HSP105 Polyclonal Antibody

Background:
Heat shock protein 105 kDais aproteinthat in humans is encoded by theHSPH1gene. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.

Research Area: Cancer, Signal Transduction

Synonyms:
Antigen NY CO 25, Antigen NY-CO-25, DKFZp686M05240, Heat shock 105kD alpha, Heat shock 105kD, Heat shock 105kD beta, Heat shock 105kDa protein 1, Heat shock 105kDa protein, Heat shock 105kDa/110kDa protein 1, Heat shock 110 kDa protein, Heat shock 110kDa protein, Heat shock protein 105 kDa, HS105, HSP105, HSP105A, HSP105B, HSP110, HSPH 1, Hsph1, KIAA0201, NY CO 25

Immunogen: Recombinant protein of human HSPH1

Swissprot: Q92598
Gene Accession: BC037553

Calculated MW: 97 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1804/sc-6241