HSP105 rabbit polyclonal, anti-human, mouse

Backgroud: function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,

Synonyms: HSPH1, HSP105, HSP110, KIAA0201, Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein

Gene Name: HSPH1

Gene ID: 10808

SwissProt ID: Q92598

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.