Hsp27 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
HSPB1(Heat shock 27kDa protein 1), also known as HSP27, is a protein that in humans is encoded by the HSPB1 gene. Stock et al.(2003) used FISH to map the HSP27 gene to 7q11.23. The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F(CMT2F) and distal hereditary motor neuropathy(dHMN).

Description:
Rabbit IgG polyclonal antibody for Heat shock protein beta-1 (HSPB1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.

Synonyms:
Heat shock 27kDa protein antibody, 28 kDa heat shock protein antibody, CMT2F antibody, DKFZp586P1322 antibody, Estrogen regulated 24 kDa protein antibody, Estrogen-regulated 24 kDa protein antibody, Heat shock 25kDa protein 1 antibody, Heat shock 27 kDa protein antibody, Heat shock 27kD protein 1 antibody, Heat shock 27kDa protein 1 antibody, Heat shock 28kDa protein 1 antibody, Heat Shock Protein 27 antibody, Heat shock protein beta 1 antibody, Heat shock protein beta-1 antibody, Heat Shock Protein27 antibody, HMN2B antibody, HS.76067 antibody, Hsp 25 antibody, Hsp 27 antibody, Hsp 28 antibody, Hsp B1 antibody, Hsp25 antibody, HSP27 antibody, Hsp28 antibody, HspB1 antibody, HSPB1_HUMAN antibody, SRP27 antibody, Stress responsive protein 27 antibody, Stress-responsive protein 27 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Hsp27(88-105aa KHEERQDEHGYISRCFTR), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence in the middle region of human Hsp27(88-105aa KHEERQDEHGYISRCFTR), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, IHC-F, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.