HSP40 Polyclonal Antibody

Background:
Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association between HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. There are five known HSP 40 family proteins.

Research Area: Cancer, Signal Transduction

Synonyms:
DnaJ (Hsp40) homolog subfmaily B member 1, DNAJ 1, DNAJ B1, DnaJ heat shock protein family (Hsp40) member B1, DnaJ homolog subfamily B member 1, DnaJ protein homolog 1, DNAJ1, DNAJB 1, Dnajb1, DNAJB1 protein, DNJB1, HDJ 1, HDJ-1, HDJ1, Heat shock 40 kDa protein 1, Heat shock 40kD protein 1, Heat shock protein 40, Hsp 40, HSP40, HSPF 1, HSPF1, Human DnaJ protein 1, Radial spoke 16 homolog B, RSPH16B, Sis1

Immunogen: Recombinant protein of human DNAJB1

Swissprot: P25685
Gene Accession: BC002352

Calculated MW: 38 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1801/sc-49988/sc-1800/sc-28845