HSP60 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Synonyms: CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13

Cellular Location: Mitochondrion matrix

Immunogen:
A synthetic peptide of human HSP60

Gene Symbol: HSP60

Gene ID: 3329

Swiss prot: P10809

Calculated MW: 65kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.