HSP70 (clone 5A6), anti-human

Protein Family: Chaperones and Folding Catalysts

Pathway and Disease: Immune System, Membrane Transport, Signal Transduction

Description:
HSP-70 (Heat shock 70 kDa protein 1) is a 70-kDa heat shock protein, a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, HSP-70 stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles. Heat shock proteins recognize non-native conformations of other proteins during translation and membrane translocation or following stress-induced damages. HSP-70 is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

Alternate Names: Heat shock 70 kDa protein 1, HSP70, HSP70.1, HSP70-1/HSP70-2, HSPA1A, HSPA1, HSPA1B

Application Notes: WB: 1:200-1:1000; IHC: 1:200-1:1000; IF: 1:200-1:1000

Accession No.: P08107

Antigen: Purified recombinant fragment of human HSP70 expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.