HSP90 beta Monoclonal Antibody

Background:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Research Area: Cancer, Signal Transduction

Synonyms:
90 kda heat shock protein beta HSP90 beta, D6S182, FLJ26984, Heat shock 84 kDa, Heat shock 90kD protein 1, beta, Heat shock 90kDa protein 1 beta, Heat shock protein 90 alpha family class B member 1, Heat shock protein 90 kDa, Heat shock protein 90kDa alpha (cytosolic) class B member 1, Heat shock protein 90kDa alpha family class B member 1, Heat shock protein beta, Heat shock protein HSP 90 beta, Heat shock protein HSP 90-beta, HS90B, HSP 84, HSP 90, HSP 90 b, HSP 90b, HSP84, HSP90 BETA, hsp90ab1, HSP90B, HSPC2, HSPCB

Immunogen: Synthetic Peptide

Swissprot: P08238

Calculated MW: 83 kDa
Observed MW: 90 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, IF 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.