HSP90 Blocking Peptide (C-term)

Background:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Other Names:
Heat shock protein HSP 90-alpha, Heat shock 86 kDa, HSP 86, HSP86, Lipopolysaccharide-associated protein 2, LAP-2, LPS-associated protein 2, Renal carcinoma antigen NY-REN-38, HSP90AA1, HSP90A, HSPC1, HSPCA

Target/Specificity:
The synthetic peptide sequence is selected from aa 644-657 of HUMAN HSP90AA1

Gene Name: HSP90AA1 (HGNC:5253)

Gene ID: 3320
Primary Accession: P07900
Other Accession: P34058; P11499; Q4R4T5; P08238; O57521; Q76LV1; P82995; P30946; O02705; P07901; Q4R4P1; P46633; P11501; Q76LV2; Q58FF7; Q9GKX7; Q9GKX8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.