HSP90 polyclonal, anti-human, mouse, rat

Background:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation.Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation

Synonyms: HSP90AA1, EL52, HEL-S-65p, Hsp103, HSP86, Hsp89, HSP89A

Cellular Location: Cytoplasm Nucleus Cell membrane

Immunogen:
Recombinant protein of human HSP90

Gene Symbol: HSP90

Gene ID: 3320

Swiss prot: P07900

Calculated MW: 90kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.