HSPA14 polyclonal, anti-human, mouse, rat

Background:
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1β, TNFα, and the chemokines IP-10, MIP-1α, MIP-1β, and normal T cell expressed and secreted (RANTES).

Alternative Name:
HSPA14, Heat shock 70 kDa protein 14, Heat shock 70kDa protein 14, Heat shock protein HSP60, Heat shock protein hsp70 related protein, HSP60, HSP70 4, HSP70 like protein 1, HSP70-like protein 1, HSP70L1, HSP7E, HSPA 14, HSPA14, MGC131990,

Application Dilution:
WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200

Specificity: HSPA14 polyclonal antibody detects endogenous levels of HSPA14 protein.

Immunogen:
recombinant protein

MW: 55 kDa

Swiss-Prot: Q0VDF9(Human) Q99M31(Mouse) Q6AYB4(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.