HSPA1A Monoclonal Antibody

Background:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Research Area: Cancer,Signal Transduction

Synonyms:
HSPA1A, HEL-S-103, HSP70-1, HSP70-1A, HSP70.1, HSP70I, HSP72, HSPA1, HSP70

Immunogen: A synthetic peptide of human HSPA1A

Swissprot: P0DMV8
Gene ID: 3303

Calculated MW: 70 kDa
Observed MW: 70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:2000-1:5000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.