HSPA1A Polyclonal Antibody

Background:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Research Area: Cancer,Signal Transduction

Synonyms:
heat shock protein family A (Hsp70) member 1A, heat shock protein family A (Hsp70) member 1B, HSP70-1B, HSP70-2, HSP70.2

Immunogen: Recombinant protein corresponding to Mouse HSP70

Swissprot: P0DMV8,Q61696,P0DMW0

Calculated MW: 70 kDa
Observed MW: 70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:300-1:800

Storage:
Store at -20°C. Avoid freeze / thaw cycles.