HSPA5 polyclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AP1335A
Catalog Number: AC-AP1335A
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB1768
Applications: FC, IF, IHC-P, WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB1768
Applications: FC, IF, IHC-P, WB
Datasheet
Request Information
Background:
In cooperation with other chaperones, HSP70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. The HSP70s in mitochondria and the endoplasmic reticulum play an additional role by providing a driving force for protein translocation. They are involved in signal transduction pathways in cooperation with HSP90. They participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Other Names:
78 kDa glucose-regulated protein, GRP-78, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, HSPA5, GRP78
Target/Specificity:
This HSPA5 antibody is generated from rabbits immunized with a recombinant protein encoding full length human HSPA5.
Antigen Type: Recombinant Protein
Gene Name: HSPA5 (HGNC:5238)
Gene ID: 3309
Primary Accession: P11021
NCBI Accession: NP_005338.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
In cooperation with other chaperones, HSP70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. The HSP70s in mitochondria and the endoplasmic reticulum play an additional role by providing a driving force for protein translocation. They are involved in signal transduction pathways in cooperation with HSP90. They participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Other Names:
78 kDa glucose-regulated protein, GRP-78, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, HSPA5, GRP78
Target/Specificity:
This HSPA5 antibody is generated from rabbits immunized with a recombinant protein encoding full length human HSPA5.
Antigen Type: Recombinant Protein
Gene Name: HSPA5 (HGNC:5238)
Gene ID: 3309
Primary Accession: P11021
NCBI Accession: NP_005338.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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