HSPBAP1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61746
Background:
HSPBAP1 (HSPB (heat shock 27 kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1. Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell. Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events. Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis. Three isoforms of HSPBAP1 exist due to alternative splicing events.
Alternative Name:
HSPB1-associated protein 1, 27 kDa heat shock protein-associated protein 1, Protein associated with small stress protein 1, HSPBAP1, PASS1
Application Dilution: WB: 1:500~1:1000
Specificity: HSPBAP1 polyclonal antibody detects endogenous levels of HSPBAP1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 330-380 of Human HSPBAP1.
MW: ~ 55 kDa
Swis Prot.: Q96EW2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
HSPBAP1 (HSPB (heat shock 27 kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1. Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell. Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events. Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis. Three isoforms of HSPBAP1 exist due to alternative splicing events.
Alternative Name:
HSPB1-associated protein 1, 27 kDa heat shock protein-associated protein 1, Protein associated with small stress protein 1, HSPBAP1, PASS1
Application Dilution: WB: 1:500~1:1000
Specificity: HSPBAP1 polyclonal antibody detects endogenous levels of HSPBAP1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 330-380 of Human HSPBAP1.
MW: ~ 55 kDa
Swis Prot.: Q96EW2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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