HTR2B Polyclonal Antibody

Background:
This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Research Area: Metabolism, Neuroscience

Synonyms:
5 HT 2B, 5 HT 2B receptor, 5 HT(2B), 5 HT2B, 5 hydroxytryptamine (serotonin) receptor 2B, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine 2B receptor, 5 hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B, 5HT(2B), 5HT2B, 5HT2F, Htr 2b, Htr2b, NP75 protein, SEROTONIN 5HT2B RECEPTOR, Serotonin receptor 2B, Stomach fundus serotonin receptor

Immunogen: Recombinant protein of human HTR2B

Swissprot: P41595
Gene Accession: BC063123

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15076/sc-15080/sc-25647