HTR3A polyclonal, anti-human, mouse, rat

Background:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms: 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3

Cellular Location: Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse

Immunogen:
Recombinant protein of human HTR3A

Gene Symbol: HTR3A

Gene ID: 3359

Swiss prot: P46098

Calculated MW: 55kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.