HTRA1 Polyclonal Antibody

Background:
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Research Area: Cancer, Signal transduction

Synonyms:
ARMD7, CARASIL, High-temperature requirement A serine peptidase 1, HtrA, HtrA serine peptidase 1, HTRA1, HTRA1, IGFBP5 protease, L56, ORF480, Protease serine 11 (IGF binding), protease serine 11, PRSS11 , Serine protease 11, Serine protease HTRA1, Serine protease HTRA1 precursor

Immunogen: Synthetic peptide of human HTRA1

Swissprot: Q92743
Gene Accession: NP002766

Calculated MW: 51 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.