HTRA2 antibody (clone 6H8), anti-human
€435.00
In stock
SKU
AC-AT2460a
Catalog Number: AC-AT2460a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT2460a">Request Information
Background:
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Other Names:
Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, HTRA2, OMI, PRSS25
Antigen Type:
Recombinant Protein
Gene Name: HTRA2
Gene ID: 27429
NCBI Accession: NP_037379.1;NP_659540.1
Primary Accession: O43464
Other Accession: BC000096
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Other Names:
Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, HTRA2, OMI, PRSS25
Antigen Type:
Recombinant Protein
Gene Name: HTRA2
Gene ID: 27429
NCBI Accession: NP_037379.1;NP_659540.1
Primary Accession: O43464
Other Accession: BC000096
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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