HTRA2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Synonyms: HtrA2, MGCA8, OMI, PARK13, PRSS25

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human HTRA2

Gene Symbol: HTRA2

Gene ID: 27429

Swiss prot: O43464

Calculated MW: 54kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.