HTRA2 Polyclonal Antibody

Background:
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience

Synonyms:
High temperature requirement protein A2, HTRA 2, HtrA like serine protease, HtrA serine peptidase 2, HtrA, E. coli, homolog of, 2, HtrA2, HTRA2, mitochondrial, Omi stress regulated endoprotease, Omi stress-regulated endoprotease, PARK 13, PARK13, Protease serine 25, PRSS 25, PRSS25, Serine protease 25, Serine protease HTRA2, Serine protease HTRA2 mitochondrial, Serine protease htra2 mitochondrial precursor, Serine protease omi, Serine proteinase OMI

Immunogen: Synthetic peptide of human HTRA2

Swissprot: O43464
Gene Accession: NP037379

Calculated MW: 49 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.